Background: Medicinal plants are important for pharmacological research and drug development. Aim and Objective: The aim objectives of present study was to evaluate the wound healing activity of seed oil of Asparagus racemosus in Excision and Incision wound models in rats. Result Discussion: The study thus demonstrated the as wound healing activity of Asparagus racemosus seed oil and found to be effective in the functional recovery of the wound. It promotes wound contraction of excision wound as compared to control group.
2. INFERTILITY: AN OBSERVATIONAL STUDY FROM THE WORK OF YAMOAH J (1989) T...
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James Yamoah
PhD., School of Theology and Ministry and the Vice President, Ghana Christian University College, Accra.
Objectives: The aim of this study was to assess and compare scientific output of research on infertility with modern day works as against a project work done by Yamoah 1989 on infertility using a case study from two health centers using herbal and orthodox medicines in the treatment of infertility inn Kumasi, Ashanti region of Ghana on the year 1989. Method: Research publications on infertility from 2011 to 2024 were retrieved from the Web of Science Core Collection (WoSCC). Pub med, Google scholar. In all about 120 articles, books and conference materials on modern day infertility diagnosis, treatment and recommendations were used. Bibliometric analyses were performed using VOSviewer software. Results: Out of the total of 120 articles related to the study of infertility, the researchers saw a sharp rise in the number of publications on the subject matter from 2013 to 2023 with a stable trend. The study conducted by Yamoah J in 1989 revealed no significant variation in the incidence of infertility among the months of any particular year. Conclusion: The researchers agree with the modern-day clinical work on infertility as done by some researcher. The researchers admit the fact as shown in epigenetics that the environment is a predictor to either infertility or fertility and with life style changes, especially avoidance of sedentary life style becomes a major intervention to break the barriers of infertility in both male and females.
3. APPLICATIONS OF ARTIFICIAL INTELLIGENCE IN SCIENCE
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Aneeta Rawat
Assistant Teacher (Sci/ Maths), Govt. High School Mittai, Barabanki - 225301, Uttar Pradesh, India.
The advanced specialties are gradually embracing artificial intelligence in complex activities, contributing to automation; biology, medicine, physics, chemistry, and ecology, as well as data analysis and perception and discovery of new opportunities. This paper on the numerous applications of AI explores how adoption of AI based methodologies is reinventing every scientific field. These areas involve artificial intelligence (AI) in enabling genomic, proteomic, and pharmaconomics as well as in formulating patient specificity drug discovery and patient-tailored therapeutic interventions that may fast-track medical outcome and diagnosis processes. AI in turn helps chemist and physicists to simulate complex systems, predict properties of molecules, and fine-tune chemical processes. By integrating AI into environmental science and space, application such as auto space mission, enhanced climate modeling and ecosystem dynamics are some of the achievements that resulted from the integration of AI. Further, the article includes some of the ethical issue with AI such as bias, privacy, and the limitations of current AI technology. A more significant level of work across disciplines, independent research initiatives, and laboratories powered by artificial intelligence is one of the possible scenarios. At any rate, artificial intelligence influences the external environment and acts as the driving force for changing the entire picture of science as well as pushing the boundaries of knowledge.
4. ADVANCEMENTS IN TADALAFIL FORMULATION AND TRANSDERMAL DELIVERY: A COMP...
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Yousuf Quraishee
Research Scholar, Faculty of Pharmacy, PK University, Thanra - 473665, Madhya Pradesh, India.
Consequently, the developments in transdermal delivery systems for Tadalafil are a shift in the management of erectile dysfunction and benign prostatic hyperplasia. The main disadvantages of conventional oral formulations are poor absorption, first-pass metabolism, and a number of side effects that may compromise patient compliance. Nonetheless, there are drawbacks associated with these formulation types, which have been overcome to a large extent by transdermal formulations such as patches and formulations at the nano scale. It has also reduced the bioavailability and steady state drug concentrations than that of transdermal Tadalafil, which increases the therapeutic efficacy. Further, the slow and sustained release typical of transdermal delivery has been linked to lessened system toxicities, thus improving patient compliance. Research work has also started to support these innovations and the potential of the transdermal Tadalafil in offering better results than the oral Tadalafil has been proved. Further studies are being conducted on the ways to improve the efficiency of Tadalafil administration, and all of them show a positive trend in this regard. As the methods of transdermal drug delivery develop all over the world, the possibility to enhance the usage of Tadalafil for patients can be seen. This shift is not only expected to increase the effectiveness of therapy but also to increase the general quality of life of patients. Subsequent studies will also be required to determine uniform transdermal formulations and elaborate on therapeutic possibilities in uncommon patient groups. Transdermal Tadalafil can be considered a new moving step in the search for which the most adequate therapeutic solution for erectile dysfunction may exist.
5. EXPLORING THE MEDICINAL BENEFITS AND THERAPEUTIC APPLICATIONS OF PHASE...
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Akash Kumar Singh
Research Scholar, Faculty of Pharmacy, PK University, Thanra - 473665, Madhya Pradesh, India.
Phaseolus vulgaris-the commercial bean-is one such staple with nutritional value recognized the world over. Besides being an important food, lately its high concentration of phytochemicals has shown some potential medicinal uses. Its bioactive components range across wide pharmacological activities. This review discusses some of the most relevant micronutrients, proteins, flavonoids, and phenolic acids contained therein. This review highlights in detail the antioxidant, antidiabetic, anti-inflammatory, anticancer, and cardioprotective actions by in vitro and in vivo studies. Also, antimicrobial and weight management application of this legume adds to its vigor as a multifaceted therapeutic agent. The toxicological properties of P. vulgaris such as toxicity via a raw form and means of ingestion and dosage have also been documented. This review demonstrates that Phaseolus vulgaris is much more than a source of caloric sustenance and seriously suggests new medical or nutraceutical possibilities. These findings underline the necessity for far more studies on this versatile legume's medicinal properties in order to employ it properly in modern healthcare.
